Adrian Lupescu

Institute of Physiology -Karls-University of Tuebingen, Germany, Tuebingen, Germania

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Născut(ă) în 1978

Interese: Microscopie de fluorescenta- Concentratia Ca2+ intracelulara- pH intracelular

Detalii:
Awards:


2001 3th PLACE at the Scientific Conference for Medical Students and Young
Doctors -Craiova,1-3 June 2001 with Conduita clinicii ORL Craiova in
rezolvarea corpilor străini traheobronşici - Adrian Lupescu , Elena Ionita

2002 HONORABLE MENTION at the 4th International Medical Conference for
Students and Young Doctors, Sibiu, 6-9 November 2003 with Investigation of the
Effect of Herbal Plant Extracts on the Lymphocyte Proliferation - Adrian Lupescu,
Torsten Boehler, Hans-H. Neumayer

2005 EXCELLENCY PRICE at MARISIENSIS - the conference for Medical Students and
Young Doctors - Tirgu Mures, 5-8 May 2005, Stimulation of Ca2+ Entry by
Parvovirus B19 Protein VP1 - Adrian Lupescu, P. A. Lang, H. Kaiser, R. Kandolf, T.
Bock, F. Lang


Publications:

1) Adrian Lupescu, Philipp Lang, Heike Kaiser, Reinhard Kandolf, Thomas Bock, Florian Lang
(2005) Phospholipase A2 activity-dependent stimulation of Ca2+ entry by human parvovirus B19
capsid protein VP1Stimulation of Ca2+ Entry by Parvovirus B19 Protein VP1 - (J Virol. 2006 Nov;80(22):11370-80. Epub 2006 Sep 6)

2) Ekaterina Shumilina, Angelika Lampert, Adrian Lupescu, Svetlana Myssina, Nathalie Strutz-
Seebohm, Guido Henke, Florian Grahammer, Peer Wulff, Dietmar Kuhl,, Florian Lang -Deranged
Kv channel regulation in fibroblasts from mice lacking the serum and glucocorticoid inducible
kinase SGK1-( Journal of Cellular Physiology J Cell Physiol. 2005 Jul;204(1):87-98)

3) Susanne Ullrich, Susanne Berchtold, Felicia Ranta, Guiscard Seebohm, Guido Henke, Adrian
Lupescu, Andreas F. Mack, Cho-Ming Chao, Jiping Su, Roland Nitschke, Dorothea Alexander,
Björn Friedrich, Peer Wulff, Dietmar Kuhl, Florian Lang (2005) - SGK1 mediated glucocorticoid
induced inhibition of insulin secretion - (Diabetes. 2005 Apr;54(4):1090-9)


4) C.-Thomas Bock*, Karin Klingel, Susanne Aberle, Anja Duechting, Adrian Lupescu, Florian Lang
and Reinhard Kandolf (2005) Human parvovirus B19: A new emerging pathogen of inflammatory
Cardiomyopathy - (Journal of Veterinary Medicine in 2005 Sept, in press 2005 )

5) Philipp A. Lang, Daniela S. Kempe, Adrian Lupescu, Kerstin Eisele, Barbara A. Klarl, Stephan M.
Huber, Thomas Wieder, Erich Gulbins, Florian Lang (2005) -Liver cell death and anemia in Wilson
disease involve acid sphingomyelinase and ceramide- (Nat Med. 2007 Feb;13(2):164-70. Epub 2007
Jan 28)


7) Stephan Verleysdonka,* Steffen Kistnera, Brigitte Pfeiffer-Guglielmia, John Wellarda, Adrian Lupescu, Julia Laskec, UlrichQuastc, Florian Langb, Mirna Rappd, Bernd Hamprechta - Glycogen metabolism in ependymal primary cultures: regulation by serotonin - (Brain Res. 2005 Oct 26;1060(1-2):89-99. Epub 2005 Oct 3)

8) Stefan Kramer, Adrian Lupescu, Kirsten Lauber, Florian Lang, Sebastian Wesselborg
Characteristics of NHE1 degradation by caspases - (In preparation)

9) Malgorzata Sobiesiak, Rebecca Lam, Katya Shumilina, Adrian Lupescu, Dietmar Kuhl , Tilo
Biedermann, Florian Lang - Impaired mast cell activation in gene targeted mice lacking the
Serum and Glucocorticoid inducible kinase SGK1 - (In preparation)





Abstracts:

1) Histopatological methods used in diagnosis of Helicobacter Pylori - 9 th International Conference for Students and Young Doctors, Gdansk, Poland, 10-12 May 2001

2) Posttraumatic chronic frontal sinusitis with subperiostal manifestation and retention of external parts - 12 th European Students Conference for Medical Students and Young Doctors at Charite, the Medical Faculty of Humboldt University in Berlin, 20-25 Nov.2001

3) Atitudini terapeutice diferenţiate în infertilitatea endocrină feminină (Differentiated therapeutic approaches in female endocrine infertility) - MEDIS 2002, The 6 th International Medical Students and Young Doctors Meeting, 16-18 th May 2002

4) Asocierea dintre infecţia herpetică şi eritemul polimorf (Association between the herpetic infection and Polymorphous Erithema) - MEDIS 2002, The 6 th International Medical Students and Young Doctors Meeting, 16-18 th May 2002

5) Sinuzita frontală cronică posttraumatică cu manifestări subperiostale şi retenţie de corpi străini (Posttraumatic Chronic frontal sinusitis with subperiostale manifestation and retention foreign corps) - Scientific Conference for Medical Students and Young Doctors -Craiova, 24-26 May 2002

6) Eritemul polimorf - locul infecţiei herpetice în etiopatologia bolii (Polymorphous Erithema- The significance of Herpetic Infection in the Etiopathology of this disease) - Scientific Conference for Medical Students and Young Doctors -Craiova, 24-26 May 2002


7) Efectele Imunomodulatorii a Extraselor din 11 Plante Naturale ( Immunomodulatory
Effects of 11 Herbal Plants ), Scientific Conference for Medical Students and Young
Doctors -Craiova, 6-8 June 2003

8) Studiul Potenţialelor Evocate Vizuale în Scleroza Multiplă (The study of evocation visual potentials in Multiple Sclerosis) - Scientific Conference for Medical Students and Young Doctors -Craiova,1-3 June 2001

9) Case presentation- BRUGADA Syndrome - MEDIS 2001 - The 5 th International Congress for Students and Young Doctors -Timisoara, 4-6 May 2001

10) Sindromul malformativ în disginezia gonadică (Malformative syndrome in
gonadal disginesis)- MEDIS 2002, The 6 th International Medical Students and
Young Doctors Meeting, 16-18 th May 2002

11) Klippel - Trenaunay Syndrome - Case presentation - MEDIS 2002, The 6 th
International Medical Students and Young Doctors Meeting, 16-18 th May 2002


12) Stimulation of Ca2+ Entry by Parvovirus B19 Protein VP1 - The 84th Annual Meeting of the
German Physiological Society Goettingen, Germany, March 6-9, 2005

13) Inhibition of Na+/H+ exchanger activity by Parvovirus B19 Protein NS1- The 84th
Annual Meeting of the German Physiological Society in München, Germany,
March 26-29, 2006

Publicaţii relevante:
• Böhler T, Nolting J, Gurragchaa P, Lupescu A, Neumayer HH, Budde K, Kamar N, Klupp J. . Tabebuia avellanedae extracts inhibit IL-2-independent T-lymphocyte activation and proliferation. Transpl Immunol. 2008 Feb; 18(4):319-23. Epub 2007 Sep 4, 2008.
• Schwab M, Lupescu A, Mota M, Mota E, Frey A, Simon P, Mertens PR, Floege J, Luft F, Asante-Poku S, Schaeffeler E, Lang F. . Association of SGK1 Gene Polymorphisms with Type 2 Diabetes. Cell Physiol Biochem. 2008; 21(1-3):151-60. Epub 2008 Jan 16, 2008.
• Philipp A Lang, Marcus Schenck, Jan P Nicolay, Jan Ulrich Becker, Daniela S Kempe, Adrian Lupescu, Saisudha Koka, Kerstin Eisele, Barbara A Klarl, Herbert Ru¨bben, Kurt W Schmid, Klaus Mann, Sibylle Hildenbrand, Harald Hefter, Stephan M Huber, Thomas Wieder. Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide. Nature Medicine, 2007.
• Waibel M, Kramer S, Lauber K, Lupescu A, Manns J, Schulze-Osthoff K, Lang F, Wesselborg S. . Mitochondria are not required for death receptor-mediated cytosolic acidification during apoptosis. . Apoptosis, 2006.
• Lupescu A, Bock CT, Lang PA, Aberle S, Kaiser H, Kandolf R, Lang F. . Phospholipase A2-Activity Dependent Stimulation of Ca2+ Entry by Human Parvovirus B19 Capsid Protein VP1. Journal of Virology, 2006.
• C. -Thomas Bock, Karin Klingel, Susanne Aberle, Anja Duechting, Adrian Lupescu, Florian Lang and Reinhard Kandolf. Human parvovirus B19: A new emerging pathogen of inflammatory. JVB 52, 2005.
• Verleysdonk S, Kistner S, Pfeiffer-Guglielmi B, Wellard J, Lupescu A, Laske J, Lang F, Rapp M, Hamprecht B. . Glycogen metabolism in rat ependymal primary cultures: Regulation by serotonin. . Brain Research, 2005.
• Susanne Ullrich, Susanne Berchtold, Felicia Ranta, Guiscard Seebohm, Guido Henke, Adrian Lupescu, Andreas F. Mack, Cho-Ming Chao, Jiping Su, Roland Nitschke, Dorothea Alexander, Björn Friedrich, Peer Wulff, Dietmar Kuhl, Florian Lang. SGK1 mediated glucocorticoid induced inhibition of insulin secretion. Diabetes, 54, pp. 1090-1099, 2005.
• Shumilina E, Lampert A, Lupescu A, Myssina S, Strutz-Seebohm N, Henke G, Grahammer F, Wulff P, Kuhl D, Lang F. -Deranged Kv channel regulation in fibroblasts from mice lacking the serum and glucocorticoid inducible kinase SGK1. Journal of Cellular Physiology in 2004 Dec 16, in press 2005, pp. Pages 87 -, 2005.

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