Rodica-Mariana ION

Universitatea Valahia/ ICECHIM, Targoviste/ Bucuresti, Romania

Institution web page: http://www.geocities.com/rodica_ion2000/irma.html
Personal web page: http://www.porphyrin.net/Porphyguests/rodica.html
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Born: 1958

Interests: porphyrins, phthalocyanines, photodynamic therapy of cancer

Details:
Full professor at Valahia University, Targoviste;
Manager at Analytic Department, ICECHIM, Bucharest
Department Director at ICECHIM, Bucharest;
Senior Scientist at ICECHIM, Bucharest:
Doctor in Chemical Sciences at Bucahrest University;
Profesor Nanomaterials at Valahia University, Targoviste;
Principal Coordinator of Working Group COST D20-0012-02;
Expert-evaluator of European Union for Programmes: COST, INTAS, FPVI.
Partner in FP6 project - DEVELONUTRI;
Specialist in Photodynamic therapy of cancer with porphyrins and phthalocyanines
Ph.D.Supervisor on Nanomaterials area

Selected publications:
• Rodica-Mariana Ion, Daniel Boda. PORPHYRIN-BASED SUPRAMOLECULAR NANOTUBES GENERATED BY AGGREGATION PROCESSES. Rev. Chim., Bucharest, 59(2), pp. 205-207, 2008.
• I. Hanyz, R. M. Ion, A. Nuta, D. Wróbel. Spectral characterisation of selected stilbentriazine dyes - Structural trans-cis isomerisation. Journal of Molecular Structure, 2008.
• RODICA-MARIANA ION, DOINA BOROS, MIHAELA-LUCIA ION, IRINA DUMITRIU, FIERASCU RADU-CLAUDIU, RADOVICI CONSTANTIN, GINA FLOREA, CRISTIANA BERCU. Combined spectral analysis (EDXRF, ICP-AES, XRD, FTIR) for characterization of bronze Roman Mirror. Metalurgia International, XIII(5), pp. 61-65, 2008.
• Maarten G. van der Horst, Gerard A. van Albada, Rodica-Mariana Ion, Ilpo Mutikainen, Urho Turpeinen, Stefania Tanase, Jan Reedijk. Extended Networks Generated from the Interaction of Rare-Earth(III) Ions and Pyridine-2-carboxamide-Based Ligands. Eur. J. Inorg. Chem. , pp. 2170- 2180, 2008.
• B. Barszcz, A. Bogucki, B. Laskowska, R. M. Ion, A. Graja. Spectral Investigations of Fullerene{Porphyrin Complexes. ACTA PHYSICA POLONICA A, 112, pp. 143-152, 2007.
• R. M. Ion, M. A. Calin. Comparative study of some nano- and micro - sensitizers. JOURNAL OF OPTOELECTRONICS AND ADVANCED MATERIALS, 9(6), pp. 1933-1938, 2007.
• S. Patachia, R. Ion, St. Varga. Porphyrin encapsulation in nanostructured hydrogels. JOURNAL OF OPTOELECTRONICS AND ADVANCED MATERIALS, 9(6), pp. 1816-1820, 2007.
• M. Neagu, G. Manda, C. Constantin, E. Radu, R. M. Ion. Synthetic porphyrins in experimental photodynamic therapy induce a different anti tumoral effect. J. Porphyrins Phthalocyanines, 11(1), pp. 58-65, 2007.
• Rodica-Mariana Ion, D. V. Brezoi, Monica Neagu, Gina Manda, and Carolina Constantin. Laser effect in photodynamic therapy of tumors. Proceedings of SPIE, 6606, 2007.
• R. M. Ion, D. V. Brezoi. A study on the photodynamic therapy of photosensitizer-coated magnetic nanoparticles. J. OPTOEL. ADV. MAT. , 9( 4), pp. 936-939, 2007.
• E. Stoykova, K. Nedkova, O. Sabotinov, R. Ion, R. Alexandrova. In vitro cytotoxicity assessment of second-generation photosensitizers for photodynamic therapy. J. Optoel. Adv. Mat. , 9(2), pp. 490-493, 2007.
• Rodica-Mariana ION, Dragos Viorel BREZOI, Ion UDREA. Sisteme supramoleculare gazda-musafir (porfirine incapsulate in macroneti) cu aplicatii biomedicale. Revista de Chimie, 57(8), pp. 886-889, 2006.
• Rodica-Mariana ION, Alexandru-Marcel IONITA, Benone CARSTOCEA. Degradarea fotochimica a riboflavinei utilizata ca medicament in terapia fotodinamica. Revista de Chimie, 57(7), pp. 718-721, 2006.
• Rodica-Mariana ION, Dragos-Viorel BREZOI. Nanocomposites Based on Polypyrrole with Porphyrin -Oxodimer. Nanotrends Journal, 2, pp. 1-11, 2006.
• Aleksandra Siejak, Danuta Wróbel, Rodica M. Ion. Study of resonance effects in copper phthalocyanines. Journal of Photochemistry and Photobiology A: Chemistry, 181(2-3), pp. 180-187, 2006.
• M. Neagu, G. Manda, C. Constantin, RM Ion. Structural differences of porphyrins in photodynamic therapy induce ditinct antineoplastic effects. In Journal of Porphyrins and Phthalocyanines, 10, p. 788. Elsevier, 2006.
• Gina Manda, Monica Neagu, Carolina Constantin and Rodica Mariana Ion. Tritium-labeled uridine incorporation in normal and tumor cells in experimental photodynamic therapy with synthetic porphyrins. Journal of Porphyrins and Phthalocyanines, 10, p. 760, 2006.
• Rodica Mariana Ion. Photodynamic therapy: a new concept and a clinical reality for medicine. Acta Bio-optica et Informatica Medica, 12(1), pp. 37-49, 2006.
• Radostina Alexandrova, Elena Stoykova, Rodica-Mariana Ion, Kristina Nedkova, Elena Ivanova, Kaloian Zdravkov, Georgi Minchev. In vitro cytotoxicity assessment of phthalocyanines on virus-transformed animal cells. Proc. SPIE Vol. 5830, p. 404-408, , 5830, pp. 404-408, 2005.
• M. A. Calin, R. M. Ion, N. Herascu. KRAMERS-KRONIG ANALYSIS OF 5, 10, 1, 20-TETRA-P-SULFONATOPHENYL-. Journal of Optoelectronics and Advanced Materials, 7(6), pp. 3155-3160, 2005.
• R. Alexandrova, E. Stoykova, RM Ion, K. Nedkova, E. Ivanova, K. Zdravkov, G. Minchev, . In vitro cytotoxicity assessment of Pc's on virus transformed animal cells. SPIE Proc. , 830, pp. 404-408, 2005.
• DV BREZOI, RM ION. Phase evolution induced by polypyrrole in ion oxide - polypyrrole nanocomposite, Senzors and Actuators. Senzors and Actuators B:Chemical, 109, pp. 171-175, 2005.
• RM ION, S. APOSTOL, . Photochemical study of porphyrin aggregates. Revista de Chimie, 56(6), pp. 607-620, 2005.
• Danuta Wróbel, Andrzej Boguta, Aleksandra Wójcik and Rodica M. Ion. Time-resolved photocurrent generation in a photoelectrochemical cell with phthalocyanine. SPECTROCHIMICA ACTA PART A: MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, Volume 61, Issue 6, pp. 1025-1278, 2005.
• Rodica-Mariana Ion, Dragos-Viorel Brezoi. New Nano-Sized Sensing Drug and Its Clinical Application. Solid State Phenomena, Vol. 106, pp. 79-82, 2005.
• Ion, R. M., Ionita, M. A., Carstocea, B., Pascu, M. L., Danaila, L., Bucur, A. . Clinical aspects of photodynamic therapy--Romanian experience. Oftalmologia (Bucharest, Romania : 1990), 48 (2), pp. 53-61, 2004.
• Boguta, A. , Wojcik, A. , Ion, R. M. , Wrobel, D. . Photothermal methods as tools for investigation of weakly interacting non-fluorescent phthalocyanines. Journal of Photochemistry and Photobiology A: Chemistry, 163(1-2),, pp. 201-207, 2004.
• Boguta, A., Wrobel, D., Bartczak, A., Swietlik, R., Stachowiak, Z., Ion, R. M. . Characterization of interfacial effects in organic macrocycles Langmuir and Langmuir-Blodgett layers studied by surface potential and FT-IR spectroscopy examination. Materials Science and Engineering B: Solid-State Materials for Advanced Technology, 113 (1),, pp. pp. 99-105, 2004.
• Alexandrova, R.; Sabotinov, O.; Stoykova, Elena V.; Ion, Rodica-Mariana; Shurulinkov, Stanislav; Minchev, Georgi. In vitro cytotoxicity assessment of [5, 10, 15, 20-tetra (4-sulfophenyl) porphyrin] on tumor and nontumor cell lines. SPIE, 5449, pp. 227-234, 2004.
• DANUTA WROBEL, ANDRZEJ BOGUTA, ALEKSANDRA WOJCIK and RODICA M. ION. Photovoltaic Behaviour of Non-Fluorescent Metal-Free Phthalocyanines. Nonlinear Optics Quantum Optics, 31 (1-4), 2004.
• Ion, R. M. , Scarlat, F. , Scarlat, Fl. , Niculescu, V. I. R. . Methylene - Blue modified polypyrrole film electrode for optoelectronic applications. Journal of Optoelectronics and Advanced Materials, 5(1), pp. 109-115, 2003.
• Gunaydin, K. , Ion, R. -M. , Scarlat, F., Scarlat, Fl. , Niculescu, V. I. R. , Macau, C. . Study of the fluorescence-quenching of Mg-TNP by anionic anthraquinones. Journal of Optoelectronics and Advanced Materials, 6(1), pp. 289-296, 2003.
• R. Alexandrova, Rodica-Mariana Ion, Elena V. Stoykova and Stanislav Shurulinkov. In vitro investigation on cytotoxic activity of TS4PP [5, 10, 15, 20-tetra (4-sulfophenyl) porphyrin]. Proceedings of SPIE, 5226, pp. 423-427, 2003.
• A. Boguta, D. Wrobel, A. Wojcik, R. M. Ion. The importance of triplet state population in electronic process of organic macrocycles. In T. Blanchowicz (ed.), 8th Workshop on Photoacoustics and Photothermics. 2003.
• M. A. Ionita, R. M. Ion, B. Carstocea. Photochemical and photodynamic properties of Vitamin B2-riboflavin in liposomes. Oftalmologia, 58(3), pp. 29-34, 2003.
• Gunaydin, K., Topcu, G., Ion, R. M. . 1, 5-dihydroxyanthraquinones and an anthrone from roots of Rumex crispus. Natural Product Letters, 16(1), pp. 65-70, 2002.
• Danuta Frckowiak, * Rodica-Mariana Ion, and Aneta Waszkowiak. Spectral Properties of Phthalocyanines Oriented in Stretched Polymer Films. J. Phys. Chem. B, , 106 (51),, pp. 13154 -131, 2002.
• Danuta Frackowiak, Krzysztof Wiktorowicz, Alfons Planner, Aneta Waszkowiak, and Rodica-Mariana Ion. The phthalocyanines applications in photodynamic therapy investigated by time-resolved and steady-state photothermal methods. International Journal of Photoenergy, 4(2), pp. 51-56, 2002.
• M. A. Ionita, R. M. Ion, B. Carstocea, V. I. R. Niculescu. Photodynamic occlusion of ocular neovascularization with B2vitamin. Oftalmologia, XLXIV(3), pp. 82-86, 2002.
• A. Boguta, D. Wrobel, A. Bartczak, R. M. Ion, R. Ries, A. Richter. Scanning force microscopy investigations of (semi)conductive surfaces coated with Lanmuir-Blodgett dye layers. Surface Science, 513, pp. 295-307, 2002.
• Wrobel, D. , Boguta, A. , Ion, R. M. . Mixtures of synthetic organic dyes in a photoelectrochemical cell. Journal of Photochemistry and Photobiology A: Chemistry, 138(1), pp. 7-22, 2001.
• Ion, Rodica-Mariana; Pascu, Mihail-Lucian. Porphyrins for photodynamic therapy of cancer. Proc SPIE, 4430, pp. 6421-6425, 2001.
• Danuta Frackowiak1, Aneta Waszkowiak1, Henryk Manikowski, 1 Rodica-Mariana Ion, Justyna Cofta and Krzysztof Wiktorowicz. The interactions of phthalocyanines with stimulated and resting human peripheral blood mononuclear cells. Acta Biochimica Polonica, 48(1), pp. 257-269, 2001.
• Danuta Wrobel, Andrzej Boguta, Rodica M. Ion. Photovoltaic effects in substituted metal-free and metallic sulfophthalocyanines in the photoelectrochemical cell. Journal of Molecular Structure, 595, pp. 127-138, 2001.
• R. M. Ion, M. Grigorescu, F. Scarlat, V. I. R. Niculescu, Fl. Scarlat. Porphyrins sensitization of DNA. Romanian Journal of Physics, 46 (9-10), pp. 637-646, 2001.
• D. Frackowiak, A. Planner, A. Waszkowiak, A. Boguta, R. M. Ion, K. Wiktorowicz. Yield of intersystem (singlet-triplet) crossing in phthalocyanines evaluated on the basis of a time in resolved photothermal method. Journal Photochemistry and Photobiology A:Chemistry, 141, pp. 101-108, 2001.
• Ion, R. -M., Grigorescu, M., Scarlat, F. S., Niculescu, A. V., Niculescu, V., Gunaydin, K. . Light, electron and photon irradiation of 5, 10, 15, 20-tetra (4-sulfophenyl) porphyrin used in cancer therapy. Journal of B. U. ON. , 5(2), pp. 201-207, 2000.
• Wrobel, D., Lukasiewicz, J., Goc, J., Waszkowiak, A., Ion, R. M. Photocurrent generation in an electrochemical cell with substituted metalloporphyrins. Journal of Molecular Structure, 555(28), pp. 407-417, 2000.
• Chirtop, E. , Mitov, I. , Ion, R. M. , Iliescu, M. . A low temperature path to the preparation of CoFc2O4 ferrite. Journal of Optoelectronics and Advanced Materials, 2(4), pp. 379-384, 2000.
• Pascu, Mihail L.; Popescu, Alina; Danaila, Leon; Carp, N.; Ion, Rodica-Mariana; Pascu, Mihaela O.; Staicu, Angela. Photodynamic therapy studies on brain tumors using nitrogen pulsed lasers. Proc. SPIE, 4166, pp. 138-144, 2000.
• Salih Agirtas, Rodica-Mariana Ion, Ozer Bekaroglu. Spectral study of the supramolecular assemblies porphyrins-phthalocyanines. Materials Science and Engineering: C, 7(2), pp. 105-110, 2000.
• Danuta Wróbel, Andrzej Boguta, and Rodica M. Ion. Spectroscopic and photoelectric studies of phthalocyanines in polyvinyl alcohol for application in solar energy conversion. International Journal of Photoenergy, 2(2), pp. 87-96, 2000.
• R. M. Ion, M. Grigorescu, F. Scarlat, V. I. R. Niculescu. The aggregation and photodegradation of TNP in radiation fields. Roum. Rep. Phys. , 52(8-9), pp. 711-716, 2000.
• R. M. Ion, M. Grigorescu, F. Scarlat, V. I. R. Niculescu, K. Gunaydin. Spectral properties and incorporation of haematoporphyrin into human blood cells. Rom. Journ. Phys. , 45(7-8), pp. 633-641, 2000.
• R. M. Ion. Porphyrins for tumor destruction in photodynamic therapy. Current Topics in Biophysics, 24(1), pp. 21-34, 2000.
• S. Agirtas, R. M. Ion, O. Bekaroglu. Spectral study of the supramolecular assemblies porphyrins-phthalocyanines. Materials Science Engineering, C7, pp. 105-110, 2000.
• Crisan, M., Zaharescu, M., Crisan, D., Ion, R. M. Vanadium Doped Sol-Gel TiO2 Coatings. Journal of Sol-Gel Science and Technology, 13(1-3), pp. 775-778, 1999.
• Ion, R. -M., Yilmaz, I., Bekaroglu, O. . Supramolecular assemblies of pyridyl porphyrin and diazadithia phthalocyanine. Journal of the Serbian Chemical Society, 64(7-8), pp. 453-462, 1999.
• RM Ion. Spectral Analysis of the Porphyrins Incorporation into Human Blood. Journal of Biomedical Optics, 4(3), pp. 319-326, 1999.
• Wrobel, D. , Goc, J., Ion, R. M. . Photovoltaic and spectral properties of tetraphenyloporphyrin and metallotetraphenyloporphyrin dyes. Journal of Molecular Structure, 450(1-3), pp. 239-246, 1998.
• Wrobel, D. , Hanyz, I. , Bartkowiak, R. , Ion, R. M. . Fluorescence and Time-Resolved Delayed Luminescence of Porphyrins in Organic Solvents and Polymer Matrices. Journal of Fluorescence, 8(3), pp. 191-198, 1998.
• Ion, R. -M. , Planner, A., Wiktorowicz, K. , Frackowiak, D. . The incorporation of various porphyrins into blood cells measured via flow cytometry, absorption and emission spectroscopy. Acta Biochimica Polonica, 45(3), pp. 833-845, 1998.
• Ion, R. -M., Blair, D. F. , Radovici, O. . Spectral properties of methylene blue modified polypyrrole film. Journal of the Serbian Chemical Society, 62(11), pp. 1063-1068, 1997.
• Coca, S., Dimonie, M., Dragutan, V., Ion, R. M., Popescu, L., Teodorescu, M., Moise, F., Vasilescu, A. Ring-opening polymerization of cycloolefin induced by tungsten porphyrinates. Journal of Molecular Catalysis, 90(1-2), pp. 101-110, 1994.

Publications from the ISI database, indexed between 2002-2006, produced in Romania:
• Frackowiak, D; Wiktorowicz, K; Planner, A; Waszkowiak, A; Ion, RM, The phthalocyanines applications in photodynamic therapy investigated by time-resolved and steady-state photothermal methods. INTERNATIONAL JOURNAL OF PHOTOENERGY, 4 (2), pp. 51-56, 2002.
• Boguta, A; Wrobel, D; Bartczak, A; Ion, RM; Ries, R; Richter, A, Scanning force microscopy investigations of (semi)conductive surfaces coated with Langmuir-Blodgett dye layers. SURFACE SCIENCE, 513 (2), pp. 295-307, 2002.
• Gunaydin, K; Topcu, G; Ion, RM, 1,5-dihydroxyanthraquinones and an anthrone from roots of Rumex crispus. NATURAL PRODUCT LETTERS, 16 (1), pp. 65-70, 2002.
• Ion, RM; Scarlat, F; Scarlat, F; Niculescu, VIR, Methylene - Blue modified polypyrrole film electrode for optoelectronic applications. JOURNAL OF OPTOELECTRONICS AND ADVANCED MATERIALS, 5 (1), pp. 109-115, 2003.
• Frackowiak, D; Ion, RM; Waszkowiak, A, Spectral properties of phthalocyanines oriented in stretched polymer films. JOURNAL OF PHYSICAL CHEMISTRY B, 106 (51), pp. 13154-13160, 2002.
• Boguta, A; Wrobel, D; Bartczak, A; Swietlik, R; Stachowiak, Z; Ion, RM, Characterization of interfacial effects in organic macrocycles Langmuir and Langmuir-Blodgett layers studied by surface potential and FT-IR spectroscopy examination. MATERIALS SCIENCE AND ENGINEERING B-SOLID STATE MATERIALS FOR ADVANCED TECHNOLOGY, 113 (1), pp. 99-105, 2004.
• Boguta, A; Wojcik, A; Ion, RM; Wrobel, D, Photothermal methods as tools for investigation of weakly interacting non-fluorescent phthalocyanines. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 163 (1-2), pp. 201-207, 2004.
• Gunaydin, K; Ion, RM; Scarlat, F; Scarlat, F; Niculescu, VIR; Macau, C, Study of the fluorescence-quenching of Mg-TNP by anionic anthraquinones. JOURNAL OF OPTOELECTRONICS AND ADVANCED MATERIALS, 6 (1), pp. 289-296, 2004.
• Ion, RM; Brezoi, DV, New nano-sized sensing drug and its clinical application. FROM NANOPOWDERS TO FUNCTIONAL MATERIALS. SOLID STATE PHENOMENA, 106, pp. 79-82, 2005.
• Brezoi, DV; Ion, RM, Phase evolution induced by polypyrrole in iron oxide-polypyrrole nanocomposite. SENSORS AND ACTUATORS B-CHEMICAL, 109 (1), pp. 171-175, 2005.
• Ion, RM; Apostol, S, Photochemical study of porphyrin aggregates. REVISTA DE CHIMIE, 56 (6), pp. 607-610, 2005.
• Wrobel, D; Boguta, A; Wojcik, A; Ion, RM, Time-resolved photocurrent generation in a photoelectrochemical cell with phthalocyanine. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 61 (6), pp. 1127-1132, 2005.
• Ion, RM; Scarlat, F, Non-conventional methods for porphyrins synthesis. REVISTA DE CHIMIE, 55 (11), pp. 900-904, 2004.
• Ion, RM; Ionita, AM; Carstocea, B, Photochemical degradation of riboflavin used as drug into photodynamic therapy. REVISTA DE CHIMIE, 57 (7), pp. 718-721, 2006.
• Ion, RM; Brezol, DV; Udrea, I, 'Host-Guest' supramolecular systems (encapsulated porphyrins in macronets) with biomedical applications. REVISTA DE CHIMIE, 57 (8), pp. 886-889, 2006.
• Siejak, A; Wrobel, D; Ion, RM, Study of resonance effects in copper phthalocyanines. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 181 (2-3), pp. 180-187, 2006.
• Calin, MA; Ion, RM; Herascu, N, Kramers-Kronig analysis of 5,10,1,20-tetra-p-sulfonato-phenyl-porphyrin (TSPP) as photosensitizer for photodynamic therapy. JOURNAL OF OPTOELECTRONICS AND ADVANCED MATERIALS, 7 (6), pp. 3155-3160, 2005.
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