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Dorin Toader
Astrazeneca R& D Boston,
Waltham, Statele Unite ale Americii
Pagina web a instituției:
http://www.astrazeneca-us.com/default.asp
Trimite un email
Născut(ă) în
1961
Interese:
Chimie organica, chimie medicinala, combinatoriala, medicamente
Detalii:
In prezent lucrez in domeniul cercetarii de medicamente cu indicatie oncologica.
Am obtinut doctoratul in chimie organica cu Profesorul AR Katritzky lucrind in domeniul chimiei heterociclice. Am absolvit Institutul Politehnic bucuresti, Facultatea de Tehnologie Chimica in 1985.
Publicații relevante:
• Black, Emma; Breed, Jason; Breeze, Alexander L.; Embrey, Kevin; Garcia, Robert; Gero, Thomas W.; Godfrey, Linda; Kenny, Peter W.; Morley, Andrew D.; Minshull, Claire A.; Pannifer, Andrew D.; Read, Jon; Rees, Amanda; Russell, Daniel J.; Toader, Dorin; Tuck. Structure-based design of protein tyrosine phosphatase-1B inhibitors. Bioorganic & Medicinal Chemistry Letters, 15(10), pp. 2503-2507, 2005.
• Katritzky, A. R.; Toader, D. . The Preparation of Mono-, 1, 1-Di- and Trisubstituted Ethylenes by Benzotriazole Methodology. Synlett, 4, pp. 458-466, 2001.
• Katritzky, Alan R.; Serdyuk, Larisa; Chassaing, Christophe; Toader, Dorin; Wang, Xiaojing; Forood, Behrouz; Flatt, Brenton; Sun, Congcong; Vo, Kim. Syntheses of 2-Alkylamino- and 2-Dialkylamino-4, 6-diarylpyridines and 2, 4, 6-Trisubstituted Pyrimidines Using Solid-Phase-Bound Chalcones. J. Comb. Chem. , 2(2), pp. 182-185, 2000.
• Katritzky, Alan R.; Toader, Dorin; Chassaing, Christophe; Aslan, Diana C. . Masked 2-Arylacroleins: Versatile Three-Carbon Units for Organic Synthesis. J. Org. Chem. , 64(16), pp. 6080-6084, 1999.
• Katritzky, Alan R.; Toader, Dorin. First General Synthesis of (p-Nitroaryl)diarylmethanes via Vicarious Nucleophilic Substitution of Hydrogen. . J. Org. Chem. , 62(12), pp. 4137-4141, 1997.
• Katritzky, Alan R.; Toader, Dorin; Watson, Karen; Kiely, John S. . New synthesis of SASRIN resin. Tetrahedron Lett. , 38(45), pp. 7849-7850, 1997.
• Katritzky, Alan R.; Toader, Dorin. Masked a-Arylalkenyllithium Reagents for Efficient Syntheses of Functionalized Monosubstituted and 1, 1-Disubstituted Ethylenes. . J. Am. Chem. Soc. , 119(39), pp. 9321-9322, 1997.
• Katritzky, Alan R.; Toader, Dorin; Xie, Linghong. Efficient transformation of aldehydes and ketones into one-carbon homologated carboxylic acids. . Synthesis, 12, pp. 1425-1427, 1996.
Teze și dizertații:
• Toader, Dorin. Carbon-carbon bond-forming reactions: insertion, olefination and nucleophilic substitution of hydrogen in arenes. 1997.
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